| CAMPEONATO PRIMERA DIVISION 2021 | ||||
| 1º Fecha | ||||
| 16-jul-2021 | Santa Fe | Union | 1 | Marquez |
| Boca Juniors | 1 | Obando | ||
| 16-jul-2021 | Junin | Sarmiento | 0 | |
| Estudiantes | 3 | Apaolaza (2), Castro | ||
| 17-jul-2021 | Mar del Plata | Aldosivi | 0 | |
| Patronato | 2 | Sosa, Leys | ||
| 17-jul-2021 | Rosario | Newell's Old Boys | 3 | Compagnucci, Garro, Cristaldo |
| Talleres | 2 | Santos, Auzqui | ||
| 17-jul-2021 | Lanus | Lanus | 4 | Sand (2, 1P), Lopez, Malcorra |
| Atletico Tucuman | 2 | Heredia, Carrera | ||
| 17-jul-2021 | La Plata | Gimnasia y Esgrima | 2 | Perez, Fratta |
| Platense | 2 | Mansilla, Tissera | ||
| 17-jul-2021 | Buenos Aires | Velez Sarsfield | 0 | |
| Racing Club | 0 | |||
| 18-jul-2021 | Buenos Aires | Huracan | 2 | Triverio, Hezze |
| Defensa y Justicia | 1 | Barrios | ||
| 18-jul-2021 | Avellaneda | Arsenal | 1 | Carabajal |
| San Lorenzo | 1 | Fernandez | ||
| 18-jul-2021 | Buenos Aires | River Plate | 1 | Suarez |
| Colon | 2 | Aliendro, Goez | ||
| 18-jul-2021 | Avellaneda | Independiente | 0 | |
| Argentinos Juniors | 0 | |||
| 19-jul-2021 | Santiago | Central Cordoba | 1 | Gimenez (P) |
| del Estero | Banfield | 1 | Galoppo | |
| 19-jul-2021 | Mendoza | Godoy Cruz | 2 | Leyes, Bullaude |
| Rosario Central | 1 | Caraglio | ||
| 2º Fecha | ||||
| 23-jul-2021 | San Miguel | Atletico Tucuman | 1 | Carrera |
| de Tucuman | Huracan | 0 | ||
| 23-jul-2021 | Vicente Lopez | Platense | 0 | |
| Aldosivi | 1 | Guzman | ||
| 24-jul-2021 | Santa Fe | Colon | 1 | Farias (P) |
| Lanus | 4 | Gonzalez, Sand (2), Lopez | ||
| 24-jul-2021 | Buenos Aires | San Lorenzo | 1 | Sabella |
| Central Cordoba | 0 | |||
| 24-jul-2021 | Avellaneda | Racing Club | 0 | |
| Gimnasia y Esgrima | 0 | |||
| 24-jul-2021 | Lomas de Zamora | Banfield | 0 | |
| Boca Juniors | 0 | |||
| 25-jul-2021 | Florencio Varela | Defensa y Justicia | 1 | Merentiel |
| Godoy Cruz | 2 | Lomonaco, Ojeda | ||
| 25-jul-2021 | Parana | Patronato | 2 | Sosa, Nievas |
| Sarmiento | 0 | |||
| 25-jul-2021 | Rosario | Rosario Central | 1 | Vecchio |
| Velez Sarsfield | 0 | |||
| 25-jul-2021 | Buenos Aires | River Plate | 4 | Romero, Suarez, De la Cruz, Diaz |
| Union | 0 | |||
| 25-jul-2021 | La Plata | Estudiantes | 0 | |
| Independiente | 1 | Insaurralde | ||
| 26-jul-2021 | Cordoba | Talleres | 2 | Auzqui, Valoyes |
| Arsenal | 0 | |||
| 26-jul-2021 | Buenos Aires | Argentinos Juniors | 1 | Villalba |
| Newell's Old Boys | 0 | |||
| 3º Fecha | ||||
| 27-jul-2021 | Buenos Aires | Huracan | 1 | Candia (P) |
| Colon | 1 | Morelo | ||
| 27-jul-2021 | Mar del Plata | Aldosivi | 0 | |
| Racing Club | 2 | Correa, Piatti | ||
| 27-jul-2021 | Buenos Aires | Boca Juniors | 0 | |
| San Lorenzo | 2 | Peruzzi, Ortigoza (P) | ||
| 28-jul-2021 | Santa Fe | Union | 0 | |
| Banfield | 1 | Cruz | ||
| 28-jul-2021 | Mendoza | Godoy Cruz | 1 | Ramirez |
| Atletico Tucuman | 2 | Carrera, Acosta | ||
| 28-jul-2021 | Junin | Sarmiento | 1 | Gondou |
| Platense | 0 | |||
| 28-jul-2021 | Buenos Aires | Velez Sarsfield | 0 | |
| Defensa y Justicia | 0 | |||
| 28-jul-2021 | Buenos Aires | Independiente | 2 | Roa, Romero |
| Patronato | 0 | |||
| 28-jul-2021 | Lanus | Lanus | 0 | |
| River Plate | 3 | Zuculini, De la Cruz (2) | ||
| 29-jul-2021 | Santiago | Central Cordoba | 2 | Komar (A), Gimenez |
| del Estero | Talleres | 1 | Diaz | |
| 29-jul-2021 | Avellaneda | Arsenal | 1 | Sepulveda |
| Argentinos Juniors | 0 | |||
| 29-jul-2021 | La Plata | Gimnasia y Esgrima | 1 | Morales |
| Rosario Central | 0 | |||
| 29-jul-2021 | Rosario | Newell's Old Boys | 4 | Scocco, Castro (2), Giani |
| Estudiantes | 2 | Castro (2) | ||
| 4º Fecha | ||||
| 31-jul-2021 | Santa Fe | Colon | 1 | Ferreira |
| Godoy Cruz | 0 | |||
| 31-jul-2021 | Lanus | Lanus | 1 | Sand |
| Union | 1 | Acosta (A) | ||
| 31-jul-2021 | Avellaneda | Racing Club | 1 | Garre |
| Sarmiento | 0 | |||
| 31-jul-2021 | Vicente Lopez | Platense | 1 | Schott |
| Independiente | 1 | Roa | ||
| 1-ago-2021 | Florencio Varela | Defensa y Justicia | 3 | Pizzini, Bou, Contreras |
| Gimnasia y Esgrima | 2 | Fratta, Perez | ||
| 1-ago-2021 | Cordoba | Talleres | 0 | |
| Boca Juniors | 0 | |||
| 1-ago-2021 | Buenos Aires | River Plate | 1 | Romero |
| Huracan | 1 | Silva | ||
| 1-ago-2021 | Buenos Aires | San Lorenzo | 1 | Fernandez |
| Banfield | 1 | Enrique | ||
| 2-ago-2021 | Parana | Patronato | 0 | |
| Newell's Old Boys | 0 | |||
| 2-ago-2021 | Buenos Aires | Argentinos Juniors | 1 | Coronel |
| Central Cordoba | 1 | Martinez | ||
| 2-ago-2021 | Rosario | Rosario Central | 1 | Avila |
| Aldosivi | 2 | Lodico (2) | ||
| 2-ago-2021 | La Plata | Estudiantes | 4 | Godoy, Noguera, Castro, Diaz |
| Arsenal | 0 | |||
| 2-ago-2021 | San Miguel | Atletico Tucuman | 0 | |
| de Tucuman | Velez Sarsfield | 0 | ||
| 5º Fecha | ||||
| 6-ago-2021 | Junin | Sarmiento | 1 | Graciani |
| Rosario Central | 0 | |||
| 6-ago-2021 | Rosario | Newell's Old Boys | 1 | Scocco |
| Platense | 0 | |||
| 7-ago-2021 | Lomas de Zamora | Banfield | 0 | |
| Talleres | 1 | Martino | ||
| 7-ago-2021 | Santa Fe | Union | 4 | Gattoni (A), Marquez, Esquivel, Insaurralde |
| San Lorenzo | 0 | |||
| 7-ago-2021 | Buenos Aires | Huracan | 0 | |
| Lanus | 1 | Sand | ||
| 7-ago-2021 | Mendoza | Godoy Cruz | 2 | Ojeda (2, 1P) |
| River Plate | 1 | Alvarez | ||
| 8-ago-2021 | La Plata | Gimnasia y Esgrima | 1 | Aleman |
| Atletico Tucuman | 0 | |||
| 8-ago-2021 | Buenos Aires | Velez Sarsfield | 0 | |
| Colon | 1 | Farias (P) | ||
| 8-ago-2021 | Buenos Aires | Boca Juniors | 1 | Torren (A) |
| Argentinos Juniors | 1 | Romero | ||
| 8-ago-2021 | Avellaneda | Independiente | 1 | Romero |
| Racing Club | 0 | |||
| 9-ago-2021 | Avellaneda | Arsenal | 2 | Ruiz, Picco |
| Patronato | 2 | Paz, Arias | ||
| 9-ago-2021 | Mar del Plata | Aldosivi | 1 | Lodico |
| Defensa y Justicia | 0 | |||
| 9-ago-2021 | Santiago | Central Cordoba | 1 | Gimenez (P) |
| del Estero | Estudiantes | 2 | Apaolaza, Del Prete | |
| 6º Fecha | ||||
| 13-ago-2021 | Santa Fe | Colon | 1 | Meza |
| Gimnasia y Esgrima | 0 | |||
| 13-ago-2021 | Buenos Aires | Huracan | 0 | |
| Union | 0 | |||
| 14-ago-2021 | San Miguel | Atletico Tucuman | 2 | Lotti, Pereyra |
| de Tucuman | Aldosivi | 2 | Cauteruccio (2) | |
| 14-ago-2021 | Buenos Aires | Argentinos Juniors | 2 | Reniero, Carabajal (P) |
| Banfield | 0 | |||
| 14-ago-2021 | Buenos Aires | River Plate | 2 | Fernandez (P), Romero |
| Velez Sarsfield | 0 | |||
| 14-ago-2021 | Rosario | Rosario Central | 1 | Russo |
| Independiente | 2 | Romero (2) | ||
| 15-ago-2021 | Parana | Patronato | 1 | Marin |
| Central Cordoba | 0 | |||
| 15-ago-2021 | Vicente Lopez | Platense | 2 | Bogado (P), Acevedo |
| Arsenal | 1 | Farioli (P) | ||
| 15-ago-2021 | La Plata | Estudiantes | 1 | Noguera |
| Boca Juniors | 0 | |||
| 15-ago-2021 | Avellaneda | Racing Club | 2 | Scocco (A), Dominguez |
| Newell's Old Boys | 0 | |||
| 16-ago-2021 | Cordoba | Talleres | 2 | Diaz, Fertoli |
| San Lorenzo | 0 | |||
| 16-ago-2021 | Florencio Varela | Defensa y Justicia | 4 | Contreras, Pizzini, Rotondi, Barrios |
| Sarmiento | 2 | Torres (2) | ||
| 16-ago-2021 | Lanus | Lanus | 3 | Malcorra, Lopez, Sand |
| Godoy Cruz | 1 | Bullaude | ||
| 7º Fecha | ||||
| 20-ago-2021 | Mar del Plata | Aldosivi | 3 | Cauteruccio (2, 1P), Gino |
| Colon | 0 | |||
| 20-ago-2021 | Lomas de Zamora | Banfield | 1 | Datolo |
| Estudiantes | 1 | Castro | ||
| 20-ago-2021 | Junin | Sarmiento | 3 | Montoya, Cucchi, Gondou |
| Atletico Tucuman | 0 | |||
| 20-ago-2021 | Avellaneda | Independiente | 0 | |
| Defensa y Justicia | 0 | |||
| 21-ago-2021 | Santiago | Central Cordoba | 2 | Martinez, Gimenez |
| del Estero | Platense | 2 | Schott, Bettini (A) | |
| 21-ago-2021 | Mendoza | Godoy Cruz | 1 | Ojeda |
| Huracan | 1 | Lopez (A) | ||
| 21-ago-2021 | Buenos Aires | Velez Sarsfield | 5 | Bouzat, Almada, Caseres, Ortega, Centurion |
| Lanus | 1 | Belmonte | ||
| 21-ago-2021 | Avellaneda | Arsenal | 0 | |
| Racing Club | 3 | Chancalay (2), Cvitanich | ||
| 21-ago-2021 | Buenos Aires | Boca Juniors | 1 | Vazquez |
| Patronato | 0 | |||
| 22-ago-2021 | Santa Fe | Union | 1 | Garcia |
| Talleres | 2 | Retegui, Malatini | ||
| 22-ago-2021 | Rosario | Newell's Old Boys | 1 | Castro |
| Rosario Central | 1 | Martinez | ||
| 22-ago-2021 | Buenos Aires | San Lorenzo | 0 | |
| Argentinos Juniors | 1 | Reniero | ||
| 22-ago-2021 | La Plata | Gimnasia y Esgrima | 1 | Rodriguez |
| River Plate | 1 | Suarez | ||
| 8º Fecha | ||||
| 24-ago-2021 | Parana | Patronato | 1 | Delgadillo |
| Banfield | 1 | Pons | ||
| 24-ago-2021 | Santa Fe | Colon | 1 | Ferreira |
| Sarmiento | 1 | Mainero | ||
| 24-ago-2021 | San Miguel | Atletico Tucuman | 2 | Mussis, Tesuri |
| de Tucuman | Independiente | 0 | ||
| 24-ago-2021 | Avellaneda | Racing Club | 0 | |
| Central Cordoba | 0 | |||
| 25-ago-2021 | Rosario | Rosario Central | 4 | Gamba (3), Ruben |
| Arsenal | 0 | |||
| 25-ago-2021 | Lanus | Lanus | 2 | Lopez, Gonzalez |
| Gimnasia y Esgrima | 0 | |||
| 25-ago-2021 | Florencio Varela | Defensa y Justicia | 2 | Hachen, Pizzini |
| Newell's Old Boys | 0 | |||
| 25-ago-2021 | Buenos Aires | Huracan | 1 | Candia |
| Velez Sarsfield | 1 | Orellano | ||
| 25-ago-2021 | Vicente Lopez | Platense | 1 | Bertolo |
| Boca Juniors | 3 | Briasco, Gonzalez, Pavon | ||
| 26-ago-2021 | Mendoza | Godoy Cruz | 1 | Lomonaco |
| Union | 2 | Britez, Cordero | ||
| 26-ago-2021 | Buenos Aires | Argentinos Juniors | 1 | Gomez |
| Talleres | 2 | Diaz, Santos | ||
| 26-ago-2021 | La Plata | Estudiantes | 2 | Pasquini, Pellegrini |
| San Lorenzo | 0 | |||
| 26-ago-2021 | Buenos Aires | River Plate | 2 | Alvarez, Perez |
| Aldosivi | 0 | |||
| 9º Fecha | ||||
| 28-ago-2021 | La Plata | Gimnasia y Esgrima | 0 | |
| Huracan | 0 | |||
| 28-ago-2021 | Lomas de Zamora | Banfield | 2 | Datolo, Cruz |
| Platense | 4 | Mansilla (P), Tissera, Curuchet (2) | ||
| 28-ago-2021 | Avellaneda | Independiente | 3 | Soñora (2), Roa |
| Colon | 0 | |||
| 29-ago-2021 | Avellaneda | Arsenal | 0 | |
| Defensa y Justicia | 0 | |||
| 29-ago-2021 | Santiago | Central Cordoba | 2 | Gimenez, Ribas |
| del Estero | Rosario Central | 4 | Avila, Ruben (2), Almada | |
| 29-ago-2021 | Mar del Plata | Aldosivi | 2 | Cauteruccio (2, 1P) |
| Lanus | 3 | Lopez, Sand (2, 1P) | ||
| 29-ago-2021 | Buenos Aires | Velez Sarsfield | 3 | Mancuello, Breitenbruch (A), Bouzat |
| Godoy Cruz | 0 | |||
| 29-ago-2021 | Buenos Aires | Boca Juniors | 0 | |
| Racing Club | 0 | |||
| 30-ago-2021 | Santa Fe | Union | 1 | Cordero (P) |
| Argentinos Juniors | 0 | |||
| 30-ago-2021 | Rosario | Newell's Old Boys | 1 | Scocco |
| Atletico Tucuman | 2 | Mussis, Lotti | ||
| 30-ago-2021 | Buenos Aires | San Lorenzo | 3 | Fernandez, Zapata, Di Santo (P) |
| Patronato | 0 | |||
| 30-ago-2021 | Junin | Sarmiento | 1 | Alanis |
| River Plate | 2 | Carrascal, Perez | ||
| 30-ago-2021 | Cordoba | Talleres | 2 | Andujar (A), Auzqui |
| Estudiantes | 0 | |||
| 10º Fecha | ||||
| 3-sep-2021 | Mar del Plata | Defensa y Justicia | 1 | Hachen |
| Central Cordoba | 1 | Argarañaz | ||
| 3-sep-2021 | Buenos Aires | Huracan | 2 | Cristaldo, Yacob |
| Aldosivi | 0 | |||
| 4-sep-2021 | San Miguel | Atletico Tucuman | 0 | |
| de Tucuman | Arsenal | 0 | ||
| 4-sep-2021 | Lanus | Lanus | 1 | Sand |
| Sarmiento | 1 | Alanis (P) | ||
| 4-sep-2021 | Santa Fe | Colon | 1 | Farias (P) |
| Newell's Old Boys | 1 | Mansilla | ||
| 4-sep-2021 | Vicente Lopez | Platense | 1 | Mansilla |
| San Lorenzo | 1 | Di Santo | ||
| 4-sep-2021 | Rosario | Rosario Central | 1 | Avila |
| Boca Juniors | 2 | Vazquez, Torrent (A) | ||
| 5-sep-2021 | Mendoza | Godoy Cruz | 4 | Perez, Bullaude, Ojeda (2) |
| Gimnasia y Esgrima | 0 | |||
| 5-sep-2021 | Parana | Patronato | 0 | |
| Talleres | 0 | |||
| 5-sep-2021 | Avellaneda | Racing Club | 0 | |
| Banfield | 0 | |||
| 5-sep-2021 | Buenos Aires | River Plate | 1 | Romero |
| Independiente | 1 | Bustos | ||
| 6-sep-2021 | La Plata | Estudiantes | 1 | Pellegrini (P) |
| Argentinos Juniors | 1 | Florentin (P) | ||
| 6-sep-2021 | Buenos Aires | Velez Sarsfield | 4 | Orellano, Lucero, Janson, Centurion |
| Union | 0 | |||
| 11º Fecha | ||||
| 13-sep-2021 | Junin | Sarmiento | 0 | |
| Huracan | 0 | |||
| 13-sep-2021 | Mar del Plata | Aldosivi | 1 | Cauteruccio (P) |
| Godoy Cruz | 4 | Ojeda, Lemonaco, Bullaude, Lopez | ||
| 13-sep-2021 | Avellaneda | Independiente | 0 | |
| Lanus | 1 | Lopez | ||
| 13-sep-2021 | Buenos Aires | San Lorenzo | 1 | Sabella |
| Racing Club | 1 | Dominguez | ||
| 13-sep-2021 | La Plata | Gimnasia y Esgrima | 0 | |
| Velez Sarsfield | 0 | |||
| 14-sep-2021 | Cordoba | Talleres | 2 | Fertoli, Auzqui |
| Platense | 1 | Schott | ||
| 14-sep-2021 | Avellaneda | Arsenal | 0 | |
| Colon | 0 | |||
| 14-sep-2021 | Santiago | Central Cordoba | 2 | Melano (2) |
| del Estero | Atletico Tucuman | 0 | ||
| 14-sep-2021 | Buenos Aires | Boca Juniors | 0 | |
| Defensa y Justicia | 0 | |||
| 15-sep-2021 | Santa Fe | Union | 0 | |
| Estudiantes | 2 | Castro, Del Prete | ||
| 15-sep-2021 | Buenos Aires | Argentinos Juniors | 1 | Reniero |
| Patronato | 1 | Arias (P) | ||
| 15-sep-2021 | Lomas de Zamora | Banfield | 1 | Cruz |
| Rosario Central | 2 | Ruben (2) | ||
| 15-sep-2021 | Rosario | Newell's Old Boys | 1 | Scocco |
| River Plate | 4 | De la Cruz, Alvarez (2), Carrascal | ||
| 12º Fecha | ||||
| 18-sep-2021 | Mendoza | Godoy Cruz | 1 | Colman |
| Sarmiento | 1 | Torres | ||
| 18-sep-2021 | Buenos Aires | Velez Sarsfield | 3 | Almada (2), Lucero (P) |
| Aldosivi | 2 | Cerro, Cauteruccio | ||
| 18-sep-2021 | Avellaneda | Racing Club | 1 | Lopez (P) |
| Talleres | 2 | Santos, Diaz | ||
| 18-sep-2021 | San Miguel | Atletico Tucuman | 1 | Lopez (A) |
| de Tucuman | Boca Juniors | 2 | Lopez, Montes | |
| 19-sep-2021 | Parana | Patronato | 1 | Sosa |
| Estudiantes | 2 | Apaolaza, Del Prete | ||
| 19-sep-2021 | Santa Fe | Colon | 1 | Aliendro |
| Central Cordoba | 0 | |||
| 19-sep-2021 | Vicente Lopez | Platense | 0 | |
| Argentinos Juniors | 0 | |||
| 19-sep-2021 | Buenos Aires | Huracan | 0 | |
| Independiente | 1 | Soñora | ||
| 19-sep-2021 | Buenos Aires | River Plate | 1 | Mendez (A) |
| Arsenal | 0 | |||
| 20-sep-2021 | La Plata | Gimnasia y Esgrima | 1 | Guiffrey |
| Union | 0 | |||
| 20-sep-2021 | Lanus | Lanus | 1 | Lopez |
| Newell's Old Boys | 2 | Castro (2) | ||
| 20-sep-2021 | Rosario | Rosario Central | 1 | Martinez |
| San Lorenzo | 0 | |||
| 20-sep-2021 | Florencio Varela | Defensa y Justicia | 0 | |
| Banfield | 0 | |||
| 13º Fecha | ||||
| 24-sep-2021 | Junin | Sarmiento | 0 | |
| Velez Sarsfield | 1 | Lucero | ||
| 24-sep-2021 | La Plata | Estudiantes | 1 | Del Prete |
| Platense | 1 | Tissera | ||
| 25-sep-2021 | Mar del Plata | Aldosivi | 1 | Grahl |
| Gimnasia y Esgrima | 3 | Rodriguez, Contin (2) | ||
| 25-sep-2021 | Cordoba | Talleres | 4 | Tenaglia, Retegui (2), Valoyes |
| Rosario Central | 1 | Marinelli | ||
| 25-sep-2021 | Avellaneda | Arsenal | 1 | Sepulveda |
| Lanus | 0 | |||
| 25-sep-2021 | Lomas de Zamora | Banfield | 2 | Cruz |
| Atletico Tucuman | 0 | |||
| 25-sep-2021 | Santiago | Central Cordoba | 1 | Sequeira (P) |
| del Estero | River Plate | 3 | Carrascal, Alvarez, Romero | |
| 26-sep-2021 | Santa Fe | Union | 2 | Luna (2) |
| Patronato | 0 | |||
| 26-sep-2021 | Buenos Aires | San Lorenzo | 2 | Fernandez, Cabral |
| Defensa y Justicia | 1 | Pizzini | ||
| 26-sep-2021 | Avellaneda | Independiente | 1 | Marquez |
| Godoy Cruz | 4 | Ortega (A), Badaloni, Bullaude, Ojeda | ||
| 26-sep-2021 | Buenos Aires | Boca Juniors | 1 | Orsini |
| Colon | 0 | |||
| 27-sep-2021 | Buenos Aires | Argentinos Juniors | 2 | Cabrera, Mac Allister |
| Racing Club | 0 | |||
| 27-sep-2021 | Rosario | Newell's Old Boys | 0 | |
| Huracan | 1 | Coccaro | ||
| 14º Fecha | ||||
| 1-oct-2021 | Mar del Plata | Aldosivi | 1 | Britez (A) |
| Union | 2 | Gonzalez (2) | ||
| 1-oct-2021 | Lanus | Lanus | 2 | Lopez, Malcorra |
| Central Cordoba | 1 | Sequeira | ||
| 2-oct-2021 | Mendoza | Godoy Cruz | 2 | Ojeda (2) |
| Newell's Old Boys | 2 | Capasso, Cristaldo (P) | ||
| 2-oct-2021 | Vicente Lopez | Platense | 0 | |
| Patronato | 0 | |||
| 2-oct-2021 | Buenos Aires | Huracan | 1 | Coccaro |
| Arsenal | 0 | |||
| 2-oct-2021 | San Miguel | Atletico Tucuman | 0 | |
| de Tucuman | San Lorenzo | 0 | ||
| 2-oct-2021 | Buenos Aires | Velez Sarsfield | 3 | Lucero, Almada, De los Santos |
| Independiente | 3 | Romero (2), Costa | ||
| 3-oct-2021 | La Plata | Gimnasia y Esgrima | 0 | |
| Sarmiento | 1 | Torres (P) | ||
| 3-oct-2021 | Rosario | Rosario Central | 0 | |
| Argentinos Juniors | 1 | Carabajal | ||
| 3-oct-2021 | Buenos Aires | River Plate | 2 | Alvarez (2) |
| Boca Juniors | 1 | Zambrano | ||
| 3-oct-2021 | Avellaneda | Racing Club | 1 | Moreno |
| Estudiantes | 1 | Godoy | ||
| 4-oct-2021 | Mar del Plata | Defensa y Justicia | 3 | Merentiel (2), Silva |
| Talleres | 0 | |||
| 4-oct-2021 | Santa Fe | Colon | 0 | |
| Banfield | 0 | |||
| 15º Fecha | ||||
| 8-oct-2021 | Santa Fe | Union | 1 | Garcia |
| Platense | 2 | Tissera, Lomonaco | ||
| 8-oct-2021 | Santiago | Central Cordoba | 1 | Ribas |
| del Estero | Huracan | 2 | Henriquez, Ibañez | |
| 8-oct-2021 | La Plata | Estudiantes | 2 | Castro, Ayovi |
| Rosario Central | 2 | Infantino (2) | ||
| 8-oct-2021 | Rosario | Newell's Old Boys | 1 | Garro |
| Velez Sarsfield | 2 | Lucero, Tarragona | ||
| 9-oct-2021 | Buenos Aires | Argentinos Juniors | 0 | |
| Defensa y Justicia | 2 | Tripichio, Bou | ||
| 9-oct-2021 | Junin | Sarmiento | 3 | Gondou, Salvareschi, Arismendi |
| Aldosivi | 0 | |||
| 9-oct-2021 | Parana | Patronato | 1 | Vazquez |
| Racing Club | 2 | Lopez, Copetti | ||
| 9-oct-2021 | Lomas de Zamora | Banfield | 0 | |
| River Plate | 1 | Canto (A) | ||
| 9-oct-2021 | Buenos Aires | Boca Juniors | 4 | Weigandt, Almendra, Vazquez, Pavon (P) |
| Lanus | 2 | Malcorra, Braghieri | ||
| 11-oct-2021 | Avellaneda | Arsenal | 0 | |
| Godoy Cruz | 0 | |||
| 11-oct-2021 | Buenos Aires | San Lorenzo | 1 | Martegani |
| Colon | 2 | Goltz, Meza | ||
| 11-oct-2021 | Avellaneda | Independiente | 1 | Romero |
| Gimnasia y Esgrima | 1 | Carbonero | ||
| 11-oct-2021 | Cordoba | Talleres | 2 | Tenaglia, Santos |
| Atletico Tucuman | 0 | |||
| 16º Fecha | ||||
| 15-oct-2021 | Mendoza | Godoy Cruz | 0 | |
| Central Cordoba | 0 | |||
| 15-oct-2021 | Rosario | Rosario Central | 3 | Ruben, Ferreyra, Vecchio |
| Patronato | 2 | Sosa (2) | ||
| 15-oct-2021 | Avellaneda | Racing Club | 0 | |
| Platense | 1 | Lamberti | ||
| 15-oct-2021 | Buenos Aires | Velez Sarsfield | 0 | |
| Arsenal | 0 | |||
| 15-oct-2021 | Mar del Plata | Defensa y Justicia | 2 | Merentiel, Bou |
| Estudiantes | 1 | Del Prete | ||
| 16-oct-2021 | Junin | Sarmiento | 3 | Torres, Alanis, Gondou |
| Union | 4 | Gonzalez (2), Calderon, Luna | ||
| 16-oct-2021 | La Plata | Gimnasia y Esgrima | 1 | Carbonero |
| Newell's Old Boys | 0 | |||
| 16-oct-2021 | Lanus | Lanus | 1 | Lopez |
| Banfield | 1 | Cruz | ||
| 16-oct-2021 | Buenos Aires | Huracan | 0 | |
| Boca Juniors | 3 | Almendra, Vazquez, Rojo (P) | ||
| 17-oct-2021 | Santa Fe | Colon | 1 | Castro |
| Talleres | 0 | |||
| 17-oct-2021 | San Miguel | Atletico Tucuman | 4 | Ruiz, Carrera, Lotti, Ortiz |
| de Tucuman | Argentinos Juniors | 3 | Reniero, Coronel, Mac Allister | |
| 17-oct-2021 | Mar del Plata | Aldosivi | 1 | Cauteruccio |
| Independiente | 0 | |||
| 17-oct-2021 | Buenos Aires | River Plate | 3 | Alvarez (3) |
| San Lorenzo | 1 | Fernandez | ||
| 17º Fecha | ||||
| 19-oct-2021 | Vicente Lopez | Platense | 1 | Tissera |
| Rosario Central | 1 | Gamba | ||
| 19-oct-2021 | Santa Fe | Union | 1 | Calderon |
| Racing Club | 1 | Copetti | ||
| 19-oct-2021 | Parana | Patronato | 3 | Ibañez (P), Arias, Unsain (A) |
| Defensa y Justicia | 3 | Pizzini, Tripichio, Rotondi | ||
| 19-oct-2021 | Santiago | Central Cordoba | 1 | Martinez |
| del Estero | Velez Sarsfield | 2 | Mancuello, Lucero | |
| 20-oct-2021 | Avellaneda | Arsenal | 0 | |
| Gimnasia y Esgrima | 1 | Carbonero | ||
| 20-oct-2021 | Buenos Aires | San Lorenzo | 1 | Herrera |
| Lanus | 3 | Acosta, De la Vega, Gonzalez | ||
| 20-oct-2021 | La Plata | Estudiantes | 1 | Diaz |
| Atletico Tucuman | 1 | Rogel (A) | ||
| 20-oct-2021 | Lomas de Zamora | Banfield | 1 | Cruz |
| Huracan | 4 | Triverio, Acevedo, Coccaro (2) | ||
| 20-oct-2021 | Buenos Aires | Boca Juniors | 2 | Fabra, Vazquez |
| Godoy Cruz | 1 | Badaloni | ||
| 21-oct-2021 | Buenos Aires | Argentinos Juniors | 3 | Carabajal, Reniero, Coronel |
| Colon | 1 | Aliendro | ||
| 21-oct-2021 | Rosario | Newell's Old Boys | 0 | |
| Aldosivi | 0 | |||
| 21-oct-2021 | Avellaneda | Independiente | 1 | Romero |
| Sarmiento | 1 | Gondou | ||
| 21-oct-2021 | Cordoba | Talleres | 0 | |
| River Plate | 2 | Rojas, Romero | ||
| 18º Fecha | ||||
| 23-oct-2021 | La Plata | Gimnasia y Esgrima | 2 | Coronel, Rodriguez |
| Central Cordoba | 2 | Gimenez (2) | ||
| 23-oct-2021 | Mar del Plata | Defensa y Justicia | 2 | Merentiel, Loaiza |
| Platense | 1 | Tissera | ||
| 23-oct-2021 | Rosario | Rosario Central | 2 | Infantino, Ruben |
| Racing Club | 1 | Copetti | ||
| 24-oct-2021 | Mendoza | Godoy Cruz | 2 | Abrego, Bullaude |
| Banfield | 1 | Galoppo (P) | ||
| 24-oct-2021 | Santa Fe | Colon | 2 | Meza, Lertora |
| Estudiantes | 1 | Burian (A) | ||
| 24-oct-2021 | Buenos Aires | Huracan | 2 | Cristaldo, Candia |
| San Lorenzo | 1 | Di Santo | ||
| 24-oct-2021 | Buenos Aires | Velez Sarsfield | 2 | Mancuello, Tarragona |
| Boca Juniors | 0 | |||
| 25-oct-2021 | Junin | Sarmiento | 2 | Torres, Gondou |
| Newell's Old Boys | 1 | Comba | ||
| 25-oct-2021 | Mar del Plata | Aldosivi | 2 | Maciel, Lodico |
| Arsenal | 1 | Sepulveda | ||
| 25-oct-2021 | Lanus | Lanus | 3 | Lopez (2), Sand |
| Talleres | 3 | Santos (2, 1P), Auzqui (P) | ||
| 25-oct-2021 | San Miguel | Atletico Tucuman | 2 | Carrera (2) |
| de Tucuman | Patronato | 2 | Sosa (2) | |
| 25-oct-2021 | Buenos Aires | River Plate | 3 | Zuculini, Alvarez, Romero |
| Argentinos Juniors | 0 | |||
| 25-oct-2021 | Avellaneda | Independiente | 1 | Martinez |
| Union | 0 | |||
| 19º Fecha | ||||
| 29-oct-2021 | Avellaneda | Racing Club | 1 | Copetti (P) |
| Defensa y Justicia | 2 | Bou, Paredes | ||
| 29-oct-2021 | Buenos Aires | Argentinos Juniors | 0 | |
| Lanus | 1 | Acosta | ||
| 30-oct-2021 | Vicente Lopez | Platense | 4 | Tissera, Tijanovich, Lamberti, Sandoval |
| Atletico Tucuman | 1 | Heredia | ||
| 30-oct-2021 | Avellaneda | Arsenal | 1 | Antilef |
| Sarmiento | 0 | |||
| 30-oct-2021 | Cordoba | Talleres | 1 | Valoyes |
| Huracan | 0 | |||
| 30-oct-2021 | Lomas de Zamora | Banfield | 2 | Enrique, Datolo |
| Velez Sarsfield | 1 | Lucero | ||
| 30-oct-2021 | Buenos Aires | Boca Juniors | 0 | |
| Gimnasia y Esgrima | 1 | Rodriguez (P) | ||
| 31-oct-2021 | Santa Fe | Union | 3 | Luna, Machuca, Garcia |
| Rosario Central | 1 | Ruben | ||
| 31-oct-2021 | Buenos Aires | San Lorenzo | 1 | Di Santo |
| Godoy Cruz | 0 | |||
| 31-oct-2021 | Rosario | Newell's Old Boys | 1 | Bravo |
| Independiente | 0 | |||
| 31-oct-2021 | La Plata | Estudiantes | 1 | Diaz |
| de Tucuman | River Plate | 1 | Rojas | |
| 1-nov-2021 | Parana | Patronato | 2 | Gudiño, Arias |
| Colon | 0 | |||
| 1-nov-2021 | Santiago | Central Cordoba | 0 | |
| del Estero | Aldosivi | 0 | ||
| 20º Fecha | ||||
| 5-nov-2021 | Mar del Plata | Defensa y Justicia | 3 | Pizzini, Merentiel, Bou |
| Rosario Central | 0 | |||
| 5-nov-2021 | Lanus | Lanus | 1 | Malcorra (P) |
| Estudiantes | 1 | Diaz | ||
| 6-nov-2021 | Mendoza | Godoy Cruz | 0 | |
| Talleres | 2 | Perez, Komar | ||
| 6-nov-2021 | Santa Fe | Colon | 3 | Meza, Bernardi, Aliendro |
| Platense | 0 | |||
| 6-nov-2021 | Avellaneda | Independiente | 3 | Soñora, Romero, Velasco |
| Arsenal | 0 | |||
| 6-nov-2021 | San Miguel | Atletico Tucuman | 0 | |
| de Tucuman | Racing Club | 2 | Correa, Rojas | |
| 7-nov-2021 | Junin | Sarmiento | 1 | Torres |
| Central Cordoba | 3 | Riaño, Gimenez, Gallo | ||
| 7-nov-2021 | La Plata | Gimnasia y Esgrima | 0 | |
| Banfield | 1 | Enrique | ||
| 7-nov-2021 | Buenos Aires | Velez Sarsfield | 2 | Janson (2) |
| San Lorenzo | 1 | Ortega (A) | ||
| 7-nov-2021 | Buenos Aires | River Plate | 5 | Palavecino, Alvarez (4) |
| Patronato | 0 | |||
| 8-nov-2021 | Rosario | Newell's Old Boys | 1 | Perez |
| Union | 0 | |||
| 8-nov-2021 | Buenos Aires | Huracan | 1 | Triverio |
| Argentinos Juniors | 1 | Florentin | ||
| 8-nov-2021 | Mar del Plata | Aldosivi | 0 | |
| Boca Juniors | 3 | Almendra, Cardona, Villa | ||
| 21º Fecha | ||||
| 18-nov-2021 | Santa Fe | Union | 2 | Britez, Corvalan |
| Defensa y Justicia | 3 | Merentiel, Bou (2) | ||
| 18-nov-2021 | Parana | Patronato | 3 | Arias, Canteros, Sosa |
| Lanus | 2 | Sand, Malcorra | ||
| 18-nov-2021 | Lomas de Zamora | Banfield | 0 | |
| Aldosivi | 2 | Cauteruccio, Maldonado (A) | ||
| 19-nov-2021 | La Plata | Estudiante | 4 | Del Prete (2), Diaz (2, 1P) |
| Huracan | 1 | Cristaldo | ||
| 19-nov-2021 | Buenos Aires | San Lorenzo | 0 | |
| Gimnasia y Esgrima | 1 | Ramirez | ||
| 19-nov-2021 | Buenos Aires | Argentinos Juniors | 0 | |
| Godoy Cruz | 0 | |||
| 19-nov-2021 | Cordoba | Talleres | 1 | Santos (P) |
| Velez Sarsfield | 1 | Lucero | ||
| 20-nov-2021 | Rosario | Rosario Central | 3 | Ojeda, Vecchio (2) |
| Atletico Tucuman | 1 | Benitez | ||
| 20-nov-2021 | Buenos Aires | Boca Juniors | 2 | Vazquez, Fabra |
| Sarmiento | 0 | |||
| 20-nov-2021 | Santiago | Central Cordoba | 1 | Vega |
| del Estero | Independiente | 0 | ||
| 21-nov-2021 | Avellaneda | Arsenal | 3 | Antilef, Sepulveda, Farioli |
| Newell's Old Boys | 1 | Scocco | ||
| 21-nov-2021 | Avellaneda | Racing Club | 1 | Burian (A) |
| Colon | 2 | Ferreira, Beltran | ||
| 21-nov-2021 | Vicente Lopez | Platense | 0 | |
| River Plate | 1 | Alvarez | ||
| 22º Fecha | ||||
| 23-nov-2021 | La Plata | Gimnasia y Esgrima | 5 | Carbonero, Ramirez, Rodriguez, Licht (P), Aleman (P) |
| Talleres | 2 | Gerometta (A), Komar | ||
| 23-nov-2021 | Buenos Aires | Huracan | 1 | Moya |
| Patronato | 0 | |||
| 23-nov-2021 | Mar del Plata | Aldosivi | 2 | Hauche (2) |
| San Lorenzo | 0 | |||
| 23-nov-2021 | Buenos Aires | Velez Sarsfield | 2 | Gianetti, Pratto |
| Argentinos Juniors | 0 | |||
| 23-nov-2021 | Mendoza | Godoy Cruz | 1 | Ojeda |
| Estudiantes | 3 | Del Prete, Diaz (2, 1P) | ||
| 24-nov-2021 | Rosario | Newell's Old Boys | 1 | Rodriguez |
| Central Cordoba | 0 | |||
| 24-nov-2021 | Junin | Sarmiento | 0 | |
| Banfield | 0 | |||
| 24-nov-2021 | San Miguel | Atletico Tucuman | 0 | |
| de Tucuman | Defensa y Justicia | 4 | Merentiel, Hachen, Bou (P), Pizzini | |
| 24-nov-2021 | Avellaneda | Independiente | 1 | Benavidez |
| Boca Juniors | 0 | |||
| 25-nov-2021 | Avellaneda | Arsenal | 0 | |
| Union | 1 | Britez | ||
| 25-nov-2021 | Lanus | Lanus | 3 | Burdisso, Lopez, Sand |
| Platense | 3 | Tissera (2, 1P), Tijanovich | ||
| 25-nov-2021 | Santa Fe | Colon | 1 | Piovi |
| Rosario Central | 4 | Ruben (3), Vecchio | ||
| 25-nov-2021 | Buenos Aires | River Plate | 4 | Palavecino, Alvarez, Romero (2) |
| Racing Club | 0 | |||
| 23º Fecha | ||||
| 27-nov-2021 | Cordoba | Talleres | 2 | Tenaglia, Valoyes |
| Aldosivi | 0 | |||
| 27-nov-2021 | Parana | Patronato | 0 | |
| Godoy Cruz | 3 | Ojeda, Badaloni, Escobar | ||
| 27-nov-2021 | La Plata | Estudiantes | 1 | Diaz (P) |
| Velez Sarsfield | 0 | |||
| 28-nov-2021 | Rosario | Rosario Central | 2 | Ruben (2) |
| River Plate | 2 | Palavecino (2) | ||
| 28-nov-2021 | Florencio Varela | Defensa y Justicia | 1 | Merentiel |
| Colon | 1 | Castro | ||
| 28-nov-2021 | Buenos Aires | Argentinos Juniors | 3 | Avalos, Carabajal, Sandoval |
| Gimnasia y Esgrima | 0 | |||
| 29-nov-2021 | Santa Fe | Union | 3 | Garcia (3, 1P) |
| Atletico Tucuman | 0 | |||
| 29-nov-2021 | Avellaneda | Racing Club | 3 | Lopez, Sigali, Alcaraz |
| Lanus | 1 | Sand | ||
| 29-nov-2021 | Vicente Lopez | Platense | 4 | Tissera (3, 1P), Mansilla |
| Huracan | 2 | Cabral, Moya | ||
| 29-nov-2021 | Santiago | Central Cordoba | 5 | Gimenez (2, 1P), Ribas (2), Melano |
| del Estero | Arsenal | 0 | ||
| 30-nov-2021 | Buenos Aires | San Lorenzo | 1 | Fernandez |
| Sarmiento | 0 | |||
| 30-nov-2021 | Buenos Aires | Boca Juniors | 0 | |
| Newell's Old Boys | 0 | |||
| 30-nov-2021 | Lomas de Zamora | Banfield | 4 | Maldonado, Lollo, Galoppo, Soñora |
| Independiente | 1 | Maldonado (A) | ||
| 24º Fecha | ||||
| 3-dic-2021 | Santiago | Central Cordoba | 2 | Banegas, Sequeira |
| del Estero | Union | 0 | ||
| 3-dic-2021 | Santa Fe | Colon | 3 | Piovi, Bernardi, Castro |
| Atletico Tucuman | 0 | |||
| 3-dic-2021 | Buenos Aires | Velez Sarsfield | 0 | |
| Patronato | 0 | |||
| 4-dic-2021 | Avellaneda | Arsenal | 1 | Sepulveda |
| Boca Juniors | 1 | Ramirez | ||
| 4-dic-2021 | Junin | Sarmiento | 1 | Torres |
| Talleres | 2 | Garcia, Romero | ||
| 4-dic-2021 | Mendoza | Godoy Cruz | 2 | Badaloni, Ramirez |
| Platense | 2 | Tissera, Gomez | ||
| 4-dic-2021 | Buenos Aires | Huracan | 1 | Coccaro |
| Racing Club | 0 | |||
| 4-dic-2021 | Lanus | Lanus | 2 | Lopez, Sand |
| Rosario Central | 2 | Ruben (2) | ||
| 5-dic-2021 | La Plata | Gimnasia y Esgrima | 4 | Rodriguez (3, 1P), Aleman |
| Estudiantes | 4 | Del Prete, Pasquini, Noguera, Diaz | ||
| 5-dic-2021 | Avellaneda | Independiente | 1 | Romero |
| San Lorenzo | 1 | Ortigoza (P) | ||
| 5-dic-2021 | Buenos Aires | River Plate | 2 | Fernandez, Romero |
| Defensa y Justicia | 3 | Bou, Merentiel, Paredes | ||
| 6-dic-2021 | Mar del Plata | Aldosivi | 3 | Hauche, Zacaria, Braida |
| Argentinos Juniors | 2 | Avalos (2) | ||
| 6-dic-2021 | Rosario | Newell's Old Boys | 0 | |
| Banfield | 0 | |||
| 25º Fecha | ||||
| 10-dic-2021 | Vicente Lopez | Platense | 3 | Tissera, Curuchet, Schor |
| Velez Sarsfield | 2 | Lucero, Martinez | ||
| 10-dic-2021 | La Plata | Estudiantes | 2 | Noguera, Naya |
| Aldosivi | 3 | Braida, Hauche (2) | ||
| 11-dic-2021 | Santa Fe | Union | 3 | Machuca, Garcia, Gonzalez |
| Colon | 0 | |||
| 11-dic-2021 | Rosario | Rosario Central | 1 | Martinez |
| Huracan | 4 | Coccaro (2), Candia, Perez | ||
| 11-dic-2021 | Avellaneda | Racing Club | 2 | Correa (2) |
| Godoy Cruz | 1 | Bullaude | ||
| 11-dic-2021 | Parana | Patronato | 0 | |
| Gimnasia y Esgrima | 0 | |||
| 11-dic-2021 | Buenos Aires | Argentinos Juniors | 2 | Coronel, Avalos |
| Sarmiento | 0 | |||
| 11-dic-2021 | San Miguel | Atletico Tucuman | 1 | Cabral |
| de Tucuman | River Plate | 1 | Alvarez | |
| 11-dic-2021 | Buenos Aires | Boca Juniors | 8 | Pavon (2), Salvio, Zeballos (P), Gonzalez, Mancuso, Vazquez, Villa |
| Central Crodoba | 1 | Gimenez | ||
| 12-dic-2021 | Buenos Aires | San Lorenzo | 3 | Ortigoza (P), Di Santo (2) |
| Newell's Old Boys | 2 | Gonzalez, Fernandez | ||
| 12-dic-2021 | Mar del Plata | Defensa y Justicia | 2 | Rotondi, Bou |
| Lanus | 1 | Gonzalez | ||
| 12-dic-2021 | Cordoba | Talleres | 1 | Retegui |
| Independiente | 2 | Romero (P), Benavidez | ||
| 13-dic-2021 | Lomas de Zamora | Banfield | 0 | |
| Arsenal | 0 | |||